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Expression and function of toll like receptors in chronic lymphocytic leukaemia cells

✍ Scribed by Marta Muzio; Cristina Scielzo; Maria T. S. Bertilaccio; Michela Frenquelli; Paolo Ghia; Federico Caligaris-Cappio

Book ID
108676084
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
424 KB
Volume
144
Category
Article
ISSN
0007-1048

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## Abstract Toll‐like receptor (TLR) stimulation plays a crucial role in the homeostasis of human B cells. We investigated the expression of TLRs 1–9 on the cells of B‐cell chronic lymphocytic leukemia (B‐CLL) and analyzed the functional consequences of TLR stimulation on leukemic cells. We showed