Expression and function of the multidrug resistance gene product in human lymphocyte subsets
β Scribed by Markham, P.N.; Webster, K.S.; Coon, J.S.; Bines, S.D.; Chong, A.S.F.; Wang, Y.; Gebel, H.M.
- Book ID
- 121779921
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 71 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0198-8859
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
P-Glycoprotein (PGP), a product of the multidrug resistance gene (mdr), acts as an adenosine triphosphate-dependent drug efflux system in cells. Initially, PGP was found in cancer cells, but it is now known that PGP is richly distributed in the adult brain. Passage to the central nervous system is l
The objective of this study was to assess the expression of a multidrug resistance (MDR) phenotype, implicated in the cellular resistance of tumor to chemotherapy, in rheumatoid synovial membrane. Synovial membrane from 16 rheumatoid (RA) patients was studied. Six patients with osteoarthritis consti