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Expression and Characterization of a Four-α-Helix Bundle Protein That Binds the Volatile General Anesthetic Halothane

✍ Scribed by Pidikiti, Ravindernath; Shamim, Mohammad; Mallela, Krishna M. G.; Reddy, Konda S.; Johansson, Jonas S.

Book ID
127211155
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
200 KB
Volume
6
Category
Article
ISSN
1525-7797

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Towards a three-α-helix bundle protein t
Towards a three-α-helix bundle protein that binds volatile general anesthetics
✍ Gavin A. Manderson; Jonas S. Johansson 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 534 KB

## Abstract The general anesthetics halothane and chloroform are capable of binding to synthetic water‐soluble four‐α‐helix bundles, which model the putative in vivo receptors. In this study, we investigate the binding of these anesthetics to synthetic water‐soluble three‐α‐helix bundles. A series