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Expression Analysis of PAC1-R and PACAP Genes in Zebrafish Embryos

โœ Scribed by David Alexandre; Jessy Alonzeau; Brent R. Bill; Stephen C. Ekker; James A. Waschek

Book ID
107575345
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
418 KB
Volume
43
Category
Article
ISSN
0895-8696

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Opposing mitogenic regulation by PACAP in sympathetic and cerebral cortical precursors correlates with differential expression of PACAP receptor (PAC1-R) isoforms
โœ Nairu Lu; Renping Zhou; Emanuel DiCicco-Bloom ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 180 KB ๐Ÿ‘ 2 views

pathway. In contrast, cerebral cortical precursors express primarily the ''short'' (non-insert) receptor isoform and exhibit increased cAMP levels alone following PACAP treatment. Thus, opposing mitogenic regulation in sympathetic and cortical precursors correlates with differential receptor isoform