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Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland

✍ Scribed by Kamal Datta, Daniel R Hyduke, Shubhankar Suman, Bo-Hyun Moon…


Book ID
120696339
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
928 KB
Volume
7
Category
Article
ISSN
1748-717X

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We have investigated the oncogenic alterations in murine lymphomas induced by in utero exposure to gamma-radiation. The expression of the myc oncogene increased in 23% of the tumors. Alterations in the expression of the ras oncogenes and in the p53 tumor suppressor gene were not characteristic. The