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Export pumps for anionic conjugates encoded by MRP genes

✍ Scribed by Dietrich Keppler; Yunhai Cui; Jörg König; Inka Leier; Anne Nies

Book ID
117259420
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
141 KB
Volume
39
Category
Article
ISSN
0065-2571

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Absence of the canalicular isoform of th
Absence of the canalicular isoform of the MRP gene–encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome
✍ J Kartenbeck; U Leuschner; R Mayer; D Keppler 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 607 KB

The Dubin-Johnson syndrome is characterized by an patocytes into the bile. 3,4 This defect results in predomiinherited defect in the secretion of amphiphilic anionic nantly conjugated hyperbilirubinemia and a characterconjugates from hepatocytes into the bile. We have reistic secondary rise of intra