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Absence of the canalicular isoform of the MRP gene-encoded conjugate export pump from the hepatocytes in Dubin-Johnson syndrome

โœ Scribed by J Kartenbeck; U Leuschner; R Mayer; D Keppler


Book ID
118686160
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
603 KB
Volume
23
Category
Article
ISSN
0270-9139

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Absence of the canalicular isoform of th
โœ J Kartenbeck; U Leuschner; R Mayer; D Keppler ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 607 KB

The Dubin-Johnson syndrome is characterized by an patocytes into the bile. 3,4 This defect results in predomiinherited defect in the secretion of amphiphilic anionic nantly conjugated hyperbilirubinemia and a characterconjugates from hepatocytes into the bile. We have reistic secondary rise of intra

Good news on the conjugate export pump c
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cMRP IN HUMAN LIVER AND THE ABSENCE OF cMrp The human Dubin-Johnson syndrome and its animal OR cMoat IN CANALICULAR MEMBRANES OF TR 0 TRmodel, the TR 0 rat, are characterized by a chronic conju-RAT HEPATOCYTES gated hyperbilirubinemia. TR 0 rats are defective in the Mayer R, Kartenbeck J, Bu ยจchler