Evolution of physics-based methodology f
Evolution of physics-based methodology for exploring the conformational energy landscape of proteins
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Harold A. Scheraga; Jaroslaw Pillardy; Adam Liwo; Jooyoung Lee; Cezary Czaplewsk
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Article
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2001
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John Wiley and Sons
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English
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## Abstract The evolution of our physicsโbased computational methods for determining protein conformation without the introduction of secondaryโstructure predictions, homology modeling, threading, or fragment coupling is described. Initial use of a hardโsphere potential captured much of the structu