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Exploring the energy landscape of protein folding using replica-exchange and conventional molecular dynamics simulations

โœ Scribed by David A.C. Beck; George W.N. White; Valerie Daggett


Book ID
116696819
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
432 KB
Volume
157
Category
Article
ISSN
1047-8477

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## Abstract Replica exchange accelerated molecular dynamics (REXAMD) is a method that enhances conformational sampling while retaining at least one replica on the original potential, thus avoiding the statistical problems of exponential reweighting. In this article, we study three methods that can