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Exploiting Tyrosinase Expression and Activity in Melanocytic Tumors: Quercetin and the Central Role of p53

โœ Scribed by Vargas, A. J.; Sittadjody, S.; Thangasamy, T.; Mendoza, E. E.; Limesand, K. H.; Burd, R.


Book ID
121420500
Publisher
SAGE Publications
Year
2011
Tongue
English
Weight
628 KB
Volume
10
Category
Article
ISSN
1534-7354

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## Abstract Drug resistance remains a key obstacle to successful cancer treatment. The implementation of pharmacogenomics is widely proclaimed as a route to revolutionize the face of cancer therapy. Here we discuss the pharmacogenomics of the p53 tumor suppressor and its role in cancer chemosensiti