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Exploiting Binding-Induced Changes in Probe Flexibility for the Optimization of Electrochemical Biosensors

✍ Scribed by White, Ryan J.; Plaxco, Kevin W.


Book ID
118733721
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
207 KB
Volume
82
Category
Article
ISSN
0003-2700

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Ligand-Induced conformational changes in
✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 β†’ Cys permease, lactose transport is inactivated by either __N__‐ethy