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Experimental Study of Amyloidogenic Protein Adsorption to Supported Lipid Bilayers

✍ Scribed by Hellstrand, Erik; Grey, Marie; Ainalem, Marie-Louise; Nylander, Tommy; Linse, Sara; Sparr, Emma


Book ID
122317568
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
51 KB
Volume
102
Category
Article
ISSN
0006-3495

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Adsorption of melittin to a lipid bilaye
✍ J.-H. Lin; A. BaumgΓ€rtner πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 349 KB

Molecular dynamics simulations of melittin at high dilution near a fully hydrated bilayer membrane composed ofPOPC lipids have been performed for a total time of 1.36 ns. It is shown that melittin adsorbs to the membrane. In the adsorbed state the protein exhibits a well defined conformation and ori