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Experimental infection of tamarins with human non-a, non-b hepatitis virus

✍ Scribed by Dr. P. Karayiannis; M. Bamber; H. C. Thomas; P. J. Scheuer; D. Cohn; B. A. L. Hurn

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 965 KB
Volume: 11
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890110308

No coin nor oath required. For personal study only.

✦ Synopsis

Non-A, non-B (NANB) viral hepatitis was successfully transmitted to two colony-born Tamarins following inoculation with antihaemophilic factor VIII concentrate or the "H" inoculum. Both animals showed histological and ultrastructural evidence of viral hepatitis, with raised alanine aminotransferase (ALT) levels from the second week after inoculation through to the end of follow-up, 5 months later.

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