Experimental cryptococcosis in guinea pi
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Clelia M. Riera; Diana T. Masih; Rodolfo Nobile
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Article
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1983
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Springer Netherlands
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English
โ 932 KB
A guinea pig model was used to evaluate immune response to Cryptococcus neoformans. This model shared characteristics with cryptococcosis in humans. Twenty five guinea pigs injected intraperitoneally with 10(7) viable C. neoformans cells developed disseminated disease. Forty days after infection all