The spermicidal surfactant nonoxynol-9 (Igepal CO-630, GAF Corp.) and a potential impurity, lP-dioxane, were tested in the in vitro cell transformation assay using BALB/3T3 cells. Two treatment periods, 48 hr and 13 days, were used. Nonoxynol-9, tested at levels up to 10 pglml, did not induce transf
โฆ LIBER โฆ
Experimental design and statistical analysis considerations for in vitro mammalian cell transformation assays with BALB/3T3 cells
โ Scribed by Whorton, Elbert B. ;Ward, Jonathan B. ;Morris, Debra L.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1982
- Weight
- 474 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0192-2521
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Eight phthalate esters, with alcohol chain lengths of 1-11 carbon atoms and with various degrees of branching, were tested in vitro in the L5178Y mouse lymphoma mammalian cell mutation assay and in the Balb/3T3 cell transformation assay. The tests were performed as part of a voluntary testing agreem