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Experimental animal models resembling rheumatoid arthritis

✍ Scribed by Ph. M. Kaklamanis

Publisher
Springer
Year
1992
Tongue
English
Weight
613 KB
Volume
11
Category
Article
ISSN
0770-3198

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## Abstract Animal models have been used extensively in studies of rheumatoid arthritis pathogenesis. Despite the inherent limitations of all animal models, several rodent models have significantly progressed our understanding of the fundamental mechanisms underpinning rheumatoid arthritis and cont

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Rheumatoid arthritis (RA) is characterized by inflammatory synovitis and progressive destruction of cartilage and bone. While the mechanisms of cartilage destruction in RA have been evaluated in detail, much less is known about destruction of articular bone. With regard to bone, there is evidence fo