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Experimental and computational studies of determinants of membrane-protein folding

โœ Scribed by Jie Liang


Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
115 KB
Volume
6
Category
Article
ISSN
1367-5931

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โœฆ Synopsis


Recent experiments and analysis have demonstrated the important roles of hydrogen bonding and polar-polar interactions in driving transmembrane helix-helix association. Further details of the energetics of helix-helix association and interhelical packing geometry are being mapped out. Many sequence motifs and a few spatial motifs promoting helical associations have also been identified.


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