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Experiences with radioimmunoassay in the detection of HBsAg in the presence of anti-HBs

✍ Scribed by Jens-Christian Siebke

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
308 KB
Volume
3
Category
Article
ISSN
0146-6615

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✦ Synopsis

Interference from anti-HBs present during hepatitis B antigenemia caused the appearance of several false negative reactions in a competition radioimmuno-precipitation procedure. The results indicate that such interference is considerably less in the solid-phase radioimmunoassay (Ausria II) and probably causes few false negative tests. The use of pepsin treatment as a means to destroy interfering antibodies is discussed.

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HBeAg and anti-hbe detection by radioimmunoassay: Correlation with vertical transmission of hepatitis B virus in Taiwan
✍ Dr. Cladd E. Stevens; Robert A. Neurath; R. Palmer Beasley; Wolf Szmuness πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 310 KB πŸ‘ 1 views

## Abstract A sensitive radioimmunoassay technique was used to detect hepatitis B e antigen (HBeAg). A strong correlation was found between HBeAg positivity of the serum of hepatitis B surface antigen (HBsAg) carrier women in Taiwan and the subsequent development of surface antigenemia in their bab