## Abstract To investigate the relationship between viral factors and the development of chronic hepatitis B, the entire hepatitis B virus (HBV) genome of chronic carriers at different disease stages were analyzed. Eighty genotype C HBV carriers including 12 hepatitis B e antigen (HBeAg) positive a
β¦ LIBER β¦
HBeAg and anti-hbe detection by radioimmunoassay: Correlation with vertical transmission of hepatitis B virus in Taiwan
β Scribed by Dr. Cladd E. Stevens; Robert A. Neurath; R. Palmer Beasley; Wolf Szmuness
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 310 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0146-6615
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β¦ Synopsis
Abstract
A sensitive radioimmunoassay technique was used to detect hepatitis B e antigen (HBeAg). A strong correlation was found between HBeAg positivity of the serum of hepatitis B surface antigen (HBsAg) carrier women in Taiwan and the subsequent development of surface antigenemia in their babies. All babies who became chronic HBsAg carriers were born to HbeAg positive women, maternal HBeAg positivity being a better prior indication of chronic antigenemia developing in the baby than the HBsAg titer in the mother's serum.
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