Expeditious synthesis of seven-membered iminocyclitols
β Scribed by John K Gallos; Soultana C Demeroudi; Constantina C Stathopoulou; Constantinos C Dellios
- Book ID
- 104231636
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 120 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Efficient Synthesis of Seven-Membered Iminocyclitols from Glycosylenamines. -Treatment of 6-O-mesyl derivatives [cf. (I)] of glycosylenamines with base results in the formation of 1,6-aza-anhydrosugars (II) which can be easily transformed into the azepanes (IV) and (V). -(FUENTES, JOSE;
New hydroxy azepanes with an additional hydroxymethyl side arm have been conceived and their syntheses achieved from a suitably functionalized cyclohexanoid building-block extracted from the norbornyl framework. The new iminocyclitols (homoisofagomine derivatives) exhibit weak but selective inhibito