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Expedient Synthesis of N-Fused Indoles: A CF Activation and CH Insertion Approach

✍ Scribed by Kohei Fuchibe; Tsukasa Kaneko; Keiji Mori; Takahiko Akiyama


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
303 KB
Volume
48
Category
Article
ISSN
0044-8249

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## Abstract A novel palladium‐catalyzed synthesis of substituted 3‐methylene‐3__H__‐indoles from readily accessible alkynylimines has been developed. A wide variety of 2‐fluoroalkyl‐3‐methylene‐3__H__‐indoles were synthesized in moderate to good yields through this cascade carbopalladation/Cο£ΏH acti