An expedient synthesis of (Β±)-2-amino-3-
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Robert N. Hanson; Farid A. Mohamed
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Article
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1997
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Journal of Heterocyclic Chemistry
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English
β 277 KB
## Abstract The excitatory, amino acid Β±2βaminoβ3β(3βhydroxyβ5βmethylisoxazolβ4βyl)propionic acid hydrobromide was prepared in gram quantities in an 3.3% overall yield from methylbut 2βynoate. The key step was the facile preparation of methyl 3βbromoβ5βmethylisoxazoleβ4βcarboxylate.