An expedient synthesis of ellipticine vi
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Takeo Konakahara; Y.B. Kiran; Yuri Okuno; Reiko Ikeda; Norio Sakai
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Article
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2010
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Elsevier Science
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French
⚖ 269 KB
A simple and efficient total synthesis of ellipticine was developed via the Suzuki-Miyaura coupling of sterically sensitive 2-hydroxybenzeneboronic acid with a multifunctional aryl halide using Pd(OAc) 2 as a catalyst and Cu(OAc) 2 ÁH 2 O as an additive in DMSO/H 2 O as a key step followed by double