## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Expedient routes to valuable bromo-5,6-dimethoxyindole building blocks
β Scribed by Paul B. Huleatt; Sze Shiong Choo; Sheena Chua; Christina L.L. Chai
- Book ID
- 108285080
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 164 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A concise, efficient and simple route to a series of bromoindole building blocks is described. The synthetic routes are highlighted by purification-free preparation of o-nitrocinnamate intermediates and clean, modified Cadogan indole syntheses. The scope of this indole synthesis has been explored an
## Abstract The title compounds are prepared by a modified microwaveβassisted Cadogan indole synthesis.
Since the C 15 b-end-group aldehyde 10 ((b-ionylidene)acetaldehyde), an excellent intermediate in the syntheses of retinoids, can be synthesized in many ways from b-ionone, and since the corresponding acyclic C 15 y-end-group aldehyde 5 can easily be synthesized from citral (1) (Scheme 3), we applie