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Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

✍ Scribed by Li Yang; Laura M. DeBusk; Koari Fukuda; Barbara Fingleton; Brenda Green-Jarvis; Yu Shyr; Lynn M. Matrisian; David P. Carbone; P.Charles Lin

Book ID
113523470
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
1020 KB
Volume
6
Category
Article
ISSN
1535-6108

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## Abstract Tumor‐associated factors are related to increased accumulation of CD11b^+^Gr1^+^myeloid‐derived suppressor cells (MDSCs). However, the exact mechanism of how genetic factors control the expansion of MDSCs in tumor‐bearing hosts remains elusive. Herein, we found that tumor‐associated MDS