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Expanded population of CD1d-restricted Vα24+ cells in a patient with active rheumatoid arthritis

✍ Scribed by Gutowska-Owsiak, Danuta; Birchall, Martin A.; Moots, Robert J.; Christmas, Stephen E.; Pazmany, Laszlo


Book ID
122248746
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
380 KB
Volume
150
Category
Article
ISSN
1090-2341

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Clonally expanded Vα12+ (AV12S1),CD8+ T
✍ Samuel M. Behar; Chris Roy; James Lederer; Pat Fraser; Michael B. Brenner 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 889 KB

Objective. Previously, we showed that 15-20% of patients with rheumatoid arthritis (RA) have oligoclonal expansions of peripheral blood CDS+ T cells expressing T cell receptors encoded by the VJ2 (AV12S1) gene. To better understand the significance of these expansions, the present study was undertak