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Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins

✍ Scribed by Johan Lindberg; Daniel Klevebring; Wennuan Liu; Mårten Neiman; Jianfeng Xu; Peter Wiklund; Fredrik Wiklund; Ian G. Mills; Lars Egevad; Henrik Grönberg

Book ID
118440818
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
884 KB
Volume
63
Category
Article
ISSN
0302-2838

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## BACKGROUND. Unlike most other malignancies, prostate cancer metastasizes preferentially to the skeleton and elicits osteoblastic reactions. METHODS. We present a hypothesis, based upon results obtained from our laboratory and others, on the nature of progression of prostate cancer cells and the