Stereotaxic injection of GD1a gangliosid
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M.D I. Date; M. F. D. Notter; S. Y. Felten; D. L. Felten
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Article
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1991
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John Wiley and Sons
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English
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The systemic administration of 1-methyl-4-phenyl-1,2,3,64etrahydropyridine (MPTP) to young (2 months old) and aging (12 months old) C57BL/6 mice (4 X 20 mg/kg i.p. given 12 hr apart) reduced tyrosine hydroxylase (TH)-immunoreactive (IR) fibers in the striatum and reduced dopamine (DA) concentration