✦ LIBER ✦

Exhaled nitric oxide is reduced after sputum induction in asthmatic children

✍ Scribed by Giorgio L. Piacentini; Alessandro Bodini; Silvia Costella; Lucia Vicentini; Y. Suzuki; Attilio L. Boner

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 51 KB
Volume: 29
Category: Article
ISSN: 8755-6863
DOI: 10.1002/(sici)1099-0496(200006)29:6<430::aid-ppul3>3.0.co;2-0

No coin nor oath required. For personal study only.

✦ Synopsis

Exhaled nitric oxide (ENO) and eosinophil sputum markers are considered noninvasive markers of airway inflammation in asthma. The aim of this study was to evaluate whether the procedure of sputum induction can affect the level of ENO. We measured ENO before and after sputum induction by inhalation of hypertonic saline solution in 22 asthmatic children and 9 healthy controls. The ENO mean (+/- S. E.M.) value in the group of asthmatic children was reduced from a baseline value of 20.8 (+/- 3.0) ppb to 17.4 (+/- 2.4) ppb after sputum induction (P = 0.0012). In the healthy controls, the mean baseline value of ENO was 9.1 (+/- 2.1) ppb and it was reduced to 4. 8 (+/- 1.1) ppb after induction of sputum (P < 0.01). We suggest that measurements of ENO should be performed after the induction of sputum in asthmatic patients whenever both tests are done in sequence.

📜 SIMILAR VOLUMES

Exhaled nitric oxide measurements in nor

Exhaled nitric oxide measurements in normal and asthmatic children

✍ C. A. Byrnes; S. Dinarevic; E. A. Shinebourne; P. J. Barnes; A. Bush 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

The aim of this study was to determine whether we could measure exhaled nitric oxide (NO) levels in children, and whether the same pattern of exhaled NO concentrations was observed in asthmatic and normal children as had been seen in adults. Using a chemiluminescence NO analyzer, we measured NO in e

Effect of atmospheric nitric oxide (NO)

Effect of atmospheric nitric oxide (NO) on measurements of exhaled NO in asthmatic children

✍ E. Baraldi; N. M. Azzolin; C. Dario; S. Carra; R. Ongaro; P. Biban; F. Zacchello 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 44 KB 👁 2 views

The measurement of exhaled nitric oxide concentrations [NO] may provide a simple, noninvasive means for measuring airway inflammation. However, several measurement conditions may influence exhaled NO levels, and ambient NO may be one of these. We measured exhaled NO levels in 47 stable asthmatic chi

Exhaled nitric oxide in children measure

Exhaled nitric oxide in children measured by tidal breathing method: Differences between asthmatics and nonasthmatic controls

✍ M.J. Visser; M.-C.Y. de Wit; W.M.C. van Aalderen; D.S. Postma; P.L.P. Brand 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 35 KB 👁 1 views

The single-breath maneuver used to measure nitric oxide (NO) in adults cannot be performed by young children. We, therefore, developed a method of measuring NO in mixed exhaled gas collected during tidal breathing. NO was measured in mixed exhaled gas during 5 min of tidal breathing in 113 children

Exhaled nitric oxide before and after mo

Exhaled nitric oxide before and after montelukast sodium therapy in school-age children with chronic asthma: A preliminary study

✍ Donna L. Bratton; Miguel J. Lanz; Naomi Miyazawa; Carl W. White; Philip E. Silko 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 54 KB 👁 1 views

Exhaled nitric oxide (ENO) is a surrogate marker of airway inflammation in asthma. In 12 children aged 6-11 years with mild to moderate persistent asthma, ENO concentrations were measured before and after 4 weeks of treatment with montelukast sodium, a leukotriene receptor antagonist, and 2 weeks af