Four new mutations in the DNA mismatch r
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Klaus K.-F. Herfarth; Olagunju A. Ogunbiyi; Jeffrey F. Moley; Ira J. Kodner; Sam
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Article
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1998
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John Wiley and Sons
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English
โ 35 KB
๐ 2 views
Hereditary nonpolyposis colorectal cancer (HNPCC) is frequently associated with inherited mutation in one of four DNA mismatch repair genes. Somatic mutations in the same genes are also found in a subset of sporadic colorectal cancers. A defect in DNA mismatch repair results in an RER (replication e