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Excitatory amino acid antagonists and pentylenetetrazol-induced seizures during ontogenesis. I.:The effects of 2-amino-7-phosphonoheptanoate

✍ Scribed by Libor Velíšek; Regina Kusá; Martina Kulovaná; Pavel Mareš


Book ID
118344324
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
496 KB
Volume
46
Category
Article
ISSN
0024-3205

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Effect of 2-amino-7-phosphonoheptanoic a
✍ Gregory L. Holmes; James L. Thompson; G. Franklin Carl; Brian S. Gallagher; Jeff 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 488 KB

There is now considerable evidence that the N-methyl-D-aspartic acid receptor is important in the genesis of seizures. One of the selective antagonist of the NMDA receptor is 2-amino-7-phosphonoheptanoic acid (APH). In this study we evaluated the effects of intracerebroventricular (i.c.v.) administr