Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T
Exceptions to the rule: individuals with FAP specific CHRPE and mutations in exon 6 of the APC gene
โ Scribed by K. Pack; J. Smith-Ravin PhD; R. K. S. Phillips MS FRCS; S. V. Hodgson BM BCh DM FRCP
- Book ID
- 115091798
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 204 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0009-9163
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