Examining ligand-protein interactions with binding-energy landscapes
โ Scribed by Paul A. Rejto; Djamal Bouzida; Gennady M. Verkhivker
- Book ID
- 105887191
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 225 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1432-2234
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The thermodynamics of molecular recognition is investigated by a statistical energy landscape approach, where the temperature profile of the ligandแprotein binding process is determined using the weighted histogram analysis method. The analysis reveals differences in the binding energy landscapes of
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