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Examination of the signal transduction pathways leading to activation of gelatinolytic activity by interleukin-1α and Porphyromonas gingivalis in human osteosarcoma cells

✍ Scribed by Yu-Chao Chang; Shu-Chen Chu; Shun-Fa Yang; Yih-Shou Hsieh; Li-Chiu Yang; Fu-Mei Huang


Book ID
111260925
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
374 KB
Volume
39
Category
Article
ISSN
0022-3484

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Recombinant human interleukin-1 beta, a mediator of osteoblastic cell function, was found to regulate the expression of the cell adhesion receptors, integrins, on human osteosarcoma cells. Interleukin-1 beta (IL-1 beta) at picomolar concentrations, specifically elevated approximately six- to tenfold