Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats
โ Scribed by Hiroyuki Kose; Daniel H. Moralejo; Tomoe Ogino; Akira Mizuno; Takahisa Yamada; Kozo Matsumoto
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 160 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0938-8990
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The effects of the alpha and beta anomers of D-glucose on insulin release were studied in a rat model of non-insulin-dependent diabetes, which was induced by streptozotocin injection at 2 days of age. Glucose tolerance of the streptozotocin-treated rats at 8-10 weeks of age was mildly diabetic. Insu
We designed the present study to clarify whether the development of nephropathy was accelerated by a combination of hypertension and non-insulin-dependent diabetes. Spontaneously hypertensive rats with non-insulin-dependent diabetes induced by neonatal streptozotocin treatment (25.0-75.0 mg/kg) were