Synthèse des 2-amino-2-désoxy-d-arabinon
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Jean-Claude Depezay; Annie Dureault; Thierry Prange
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Article
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1983
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Elsevier Science
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English
⚖ 626 KB
Synthesis of 2-amino-2-deoxy-D-pentonolactones was performed by diastereoselective hydroxyalkylation of 2,3-0-isopropylidene-D-glyceraldehyde with ethyl isocyanoacetate, to give two oxazolines in a ratio of 7:3. Hydrolysis gave first the corresponding amides, and then the 2-amino-2-deoxypentonolacto