specificity in one patient. Restriction of ALT-cell lysis and IFN-y release against HLA-A2+ autologous and one allogeneic HLA-A2+ STS tumor target, but not other non-STS targets, was demonstrated in another patient. These data suggest that CDDP may help render STS susceptible to tumorspecific, immun
โฆ LIBER โฆ
Ex vivo activated memory T-Iymphocytes as adoptive cellular therapy of human renal cell tumour targets with potentiation by cis-diamminedichloroplatinum(II)
โ Scribed by J.E. GOLD; T.R. MASTERS; B. BABBIT; E.M. FINE; H.N. WEBER; P.D. UNGER; I. LEVENTHAL; C.D. ZIPPE; M.E. OSBAND
- Book ID
- 115199126
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 723 KB
- Volume
- 76
- Category
- Article
- ISSN
- 1464-4096
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Autolymphocyte therapy (ALT) is adoptive cellular therapy of cancer using ex vivo activation of autologous peripheral blood lymphocytes (PBL). Memory T cells are the principal effector population in ALT, with in vivo activity in patients with metastatic renal cell carcinoma (RCC) and melanoma, and e