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Evolving therapies: Farnesyltransferase inhibitors

โœ Scribed by W. Thomas Purcell; Ross C. Donehower

Book ID
107546157
Publisher
Current Science Inc.
Year
2002
Tongue
English
Weight
530 KB
Volume
4
Category
Article
ISSN
1523-3790

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Over the past few years, the idea that farnesyl-protein transferase (FPTase) inhibitors might be effective antiproliferative/antitumor agents has been realized in studies of cultured cells and in rodent models of cancer. Most of the studies with FPTase inhibitors have focused on inhibiting the growt