High-density oligonucleotide arrays
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A.P. Blanchard; R.J. Kaiser; L.E. Hood
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Article
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1996
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Elsevier Science
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English
โ 345 KB
We are attempting to produce high-density arrays of surface-bound oligonucleotides for hybridization experiments. Our approach is to mechanically miniamri~ conventional DNA synthesis chemistry. Ink-jet printer heads are used to deliver small drops of reagents to a chemically modified silicon dioxide