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Evolutionary hypervariability in the hinge region of the immunoglobulin alpha gene

โœ Scribed by Shohji Kawamura; Keiichi Omoto; Shintaroh Ueda


Book ID
119443297
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
550 KB
Volume
215
Category
Article
ISSN
0022-2836

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Two types of distributions for the frequencies of occurrence of amino acids in each position of hypervariable regions CDR-1 and CDR-2 were obtained for 2,000 immunoglobulins. The results show that some positions fit an inverse power-law distribution, while others fit an exponential-type distribution