## Abstract A proliferation of new cytotoxic and biologic agents has led to improved survival in patients with metastatic colorectal cancer (mCRC). The ability of surgery to increase longβterm survival in patients with liver and/or lung metastases also has been firmly established. It has become inc
β¦ LIBER β¦
Evolution of systemic therapy for metastatic colorectal cancerdoi
β Scribed by J Ian Geh; Yuk Ting Ma
- Book ID
- 109044092
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 50 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1462-8910
No coin nor oath required. For personal study only.
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## Abstract Options for firstβline chemotherapy in patients with metastatic colorectal carcinoma have broadened considerably with the introduction of irinotecan and oxaliplatin. Furthermore, the oral fluoropyrimidine capecitabine has demonstrated efficacy in Phase III trials and recently was approv