๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupials

โœ Scribed by Foster, Jamie W.; Brennan, Francine E.; Hampikian, Gregory K.; Goodfellow, Peter N.; Sinclair, Andrew H.; Lovell-Badge, Robin; Selwood, Lynne; Renfree, Marilyn B.; Cooper, Desmond W.; Marshall Graves, Jennifer A.

Book ID
109781997
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
643 KB
Volume
359
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.

โœฆ Synopsis

In mammals, testis determination is under the control of the testis-determining factor borne by the Y chromosome. SRY, a gene cloned from the sex-determining region of the human Y chromosome, has been equated with the testis-determining factor in man and mouse. We have used a human SRY probe to identify and clone related genes from the Y chromosome of two marsupial species. Comparisons of eutherian and metatherian Y-located SRY sequences suggest rapid evolution of these genes, especially outside the region encoding the DNA-binding HMG box. The SRY homologues, together with the mouse Ube1y homologues, are the first genes to be identified on the marsupial Y chromosome.

๐Ÿ“œ SIMILAR VOLUMES

Evolution of the mammalian Y chromosome
Evolution of the mammalian Y chromosome and sex-determining genes
โœ Graves, Jennifer A. Marshall ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 131 KB ๐Ÿ‘ 2 views

In mammals, male sex determination, as well as spermatogenesis, is controlled by genes on the Y chromosome. Evolutionary comparisons may be used to detect and test candidate genes for these functions, under the hypothesis that the rapid evolution of the mammalian Y chromosome causes it to contain fe

The role of the sex-determining region o
The role of the sex-determining region of the Y chromosome (SRY) in the etiology of 46,XX true hermaphroditism
โœ Gary D. Berkovitz; Patricia Y. Fechner; Sandra M. Marcantonio; Gail Bland; Gail ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 795 KB

The syndrome of 46,XX true hermaphroditism is a clinical condition in which both ovarian and testicular tissue are found in one individual. Both Mullerian and Wolffian structures are usually present, and external genitalia are often ambiguous. Two alternative mechanisms have been proposed to explain