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Evolution of pericentromeric heterochromatin of human X chromosome

✍ Scribed by S. Luke; T. Mathews; R. S. Verma

Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
164 KB
Volume
87
Category
Article
ISSN
0016-6707

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✦ Synopsis

An unusual large heterochromatic segment around the pericentromeric region of the X-chromosome is reported. In normal circumstances, the pericentromeric region of the X-chromosome is negative by the restriction endonuclease AluI/Giemsa technique. However, this unusual X-chromosome was found to have AluI resistant (positive) chromatin. The evolution of extra heterochromatin is a postzygotic event as substantiated by the presence of a normal cell line.

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