Patients with advanced Parkinson's disease (PD) and motor complications can obtain significant symptom improvement by deep brain stimulation (DBS) of the subthalamic nucleus (STN). Very little is published, however, about longterm effect and disease evolution during DBS. We performed a 4-year prospe
Evolution of Parkinson's disease during 4 years of bilateral deep brain stimulation of the subthalamic nucleus
✍ Scribed by Karen Østergaard; Niels Aa. Sunde
- Book ID
- 111701027
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 77 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0885-3185
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## Abstract ## Objective Parkinson's disease (PD) is a neurodegenerative disorder characterized by significant motor dysfunction and various non‐motor disturbances, including cognitive alterations. Deep brain stimulation (DBS) is an increasingly utilized therapeutic option for patients with PD tha
## Abstract Deep brain stimulation of the subthalamic nucleus is an effective treatment for advanced Parkinson's disease. The benefits of bilateral subthalamic stimulation are well documented, and some studies reported outcomes with a follow‐up of 5 to 6 years; nevertheless, few data are available
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Deep brain stimulation of the subthalamic nucleus is an accepted treatment for the motor complications of Parkinson's disease. The therapeutic mechanism of action remains incompletely understood. Although the results of deep brain stimulation are similar to the results that can be obtained by lesion