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Evidence that the N-methyl-D-aspartate subunit 1 receptor gene (GRIN1) confers susceptibility to bipolar disorder

✍ Scribed by Mundo, E; Tharmalingham, S; Neves-Pereira, M; Dalton, E J; Macciardi, F; Parikh, S V; Bolonna, A; Kerwin, R W; Arranz, M J; Makoff, A J


Book ID
110059546
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
96 KB
Volume
8
Category
Article
ISSN
1359-4184

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## Abstract The __N__‐methyl‐d‐aspartate glutamate receptors (NMDAR) act in the CNS as regulators of the release of neurotransmitters such as dopamine, noradrenaline, acetylcholine, and GABA. It has been suggested that a weakened glutamatergic tone increases the risk of sensory overload and of exag