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Evidence that Ca2+-activated K+ channels play a major role in mediating the vascular effects of iloprost and cicaprost

✍ Scribed by Lucie H Clapp; Sally Turcato; Sharon Hall; Mohjir Baloch

Book ID: 114016552
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 200 KB
Volume: 356
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(98)00549-4

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## Abstract The sperm acrosome reaction (AR) is a crucial step for mammalian fertilization. This work describes experiments to test the effect of the cesium ion (Cs^+^) and charybdotoxin (ChTX) on the Ca^2+^ or Na^+^/K^+^ ionophores stimulated hamster sperm AR in vitro. Cs^+^ and ChTX, a polypeptid