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Evidence that a Single DNA Ligase is Involved in Replication and Recombination in Yeast

✍ Scribed by Francis Fabre and Herschel Roman


Book ID
123655985
Publisher
National Academy of Sciences
Year
1979
Tongue
English
Weight
671 KB
Volume
76
Category
Article
ISSN
0027-8424

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The conditional cdc8 mutant is known to be defective, under restrictive conditions, in the elongation of DNA during synthesis. In yeast the CDC8 gene encodes thymidylate kinase. We show here that UV-induced gene conversion and gene mutation events require the participation of this CDC8 gene. Thus, t