✦ LIBER ✦
Evidence that the singleCDC8gene which encodes thymidylate kinase is involved in DNA replication, recombination and mutation in yeast
✍ Scribed by J. Żuk; H. Baranowska; D. Zaborowska
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 515 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0172-8083
No coin nor oath required. For personal study only.
✦ Synopsis
The conditional cdc8 mutant is known to be defective, under restrictive conditions, in the elongation of DNA during synthesis. In yeast the CDC8 gene encodes thymidylate kinase. We show here that UV-induced gene conversion and gene mutation events require the participation of this CDC8 gene. Thus, the same thymidylate kinase is incolved both in DNA replication and in UV-induced gene conversion and gene mutation in yeast.