## Abstract There have been conflicting reports concerning the involvement of cyclic nucleotides in sperm capacitation. We have examined the effects of micromolar concentrations of dibutyryl cyclic AMP (Bt~2~cAMP) and of the phosphodiesterase inhibitors SQ20009 and ICI63,197 on hamster sperm incuba
Evidence suggesting a role for sperm metalloendoprotease activity in penetration of zona-free hamster eggs by human sperm
✍ Scribed by Díaz-Pérez, Eneida ;Thomas, Paul ;Meizel, Stanley
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 898 KB
- Volume
- 248
- Category
- Article
- ISSN
- 0022-104X
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## Abstract The sperm acrosome reaction (AR) is a crucial step for mammalian fertilization. This work describes experiments to test the effect of the cesium ion (Cs^+^) and charybdotoxin (ChTX) on the Ca^2+^ or Na^+^/K^+^ ionophores stimulated hamster sperm AR in vitro. Cs^+^ and ChTX, a polypeptid