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Evidence of the direct effect of alendronate on the inhibitory action of 1,25-dihydroxyvitamin D3 on parathyroid hormone-related protein (PTHrP) in human osteoblasts

✍ Scribed by P Martı́nez; L Gómez; P Sabando; J Alvarez; L Carreño; I del Valle; P Esbrit; M.E Martı́nez

Book ID
117807444
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
25 KB
Volume
29
Category
Article
ISSN
8756-3282

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Parathyroid hormone-related protein (PTHrP) is strongly expressed in the epidermis and has been implicated in the regulation of growth and differentiation of keratinocytes. PTHrP has N-terminal sequence homology with parathyroid hormone (PTH) and binds to the type I PTH/PTHrP receptor, but earlier r